![]() ![]() In recent years, the use of high-throughput (HT) crystallographic techniques has enabled the delivery of structural data in a timely fashion and many drug-discovery programmes have progressed in the light of information from target-ligand complex structures (Tickle et al., 2004 Williams et al., 2005 ). The use of protein crystallography for the optimization of potential drug-candidate molecules has been well established (Congreve et al., 2005 ). ![]()
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